Mitochondrial inheritance
Known as the powerhouse of the cell, mitochondria possess their own DNA, which encodes proteins crucial for respiration. Mutations in mitochondrial genomes can be detrimental, with many genetic diseases linked to mitochondrial dysfunction. Research on plant mitochondria is also of particular interest, as mitochondrial function is crucial not only for growth and development but also for key breeding traits, such as cytoplasmic male sterility.
Recognizing its biological significance, we aim to understand a fundamental aspect of mitochondrial genetics: Inheritance. Our research is motivated from the thought experiment:
“What if we could control mitochondrial inheritance?”
Identification of cellular processes governing mitochondrial inheritance
Manipulation of mitochondrial inheritance by genetic interventions and stress applications